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Nuclear deformation can promote DNA damage even without instances of nuclear envelope ruptures

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Endothelial genotypic differences in mice models are due to the occurrence of aneuploidy and presence of abnormal centromeres, and the genetic defects, in this model, are not due to contamination form the tumour

Data adapted from Knig's research group at the University of Vienna

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The proposed minimum criteria for a qualifying data submission for the Promoting Interoperability performance category are intended to prevent penalties and errors that may occur due to unintentional submissions without data on measures overriding prior data submissions or reweighting