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In the Phase I/II trial, 27% of patients with indolent lymphoma achieved objective clinical responses at distant, noninjected tumor sites following intratumoral injection of the TLR9 agonist PF-3512676 combined with low-dose radiotherapy, including one complete and three partial responses

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Uzun L, Kokten N, Cam OH, Kalcioglu MT, Ugur MB, Tekin M, et al