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PMID 15671130

NOV11 Sequence Analysis SEQ ID NO: 47 1024 bp NOV l la, GACTCGTCTCAGGCCAGTTGCAGCCTTCTCAGCCAAACGCCGACCAAGGAAAACTCAC CG I 10725- TACCATGAGAATTGCAGTGATTTGCTTTTGCCTCCTAGGCATCACCTGTGCCATACCA 01 DNA GTTAAACAGGCTGATTCTGGAAGTTCTGAGGAAAAGCAGCTTTACAACAAATACCCAG ATGCTGTGGCCACATGGCTAAACCCTGACCCATCTCAGAAGCAGAATCTCCTAGCCCC Sequence ACAGAATGCTGTGTCCTCTGAAGAAACCAATGACTTTAAACAAGAGACCCTTCCAAGT AAGTCCAACGAAAGCCATGACCACATGGATGATATGGATGATGAAGATGATGATGACC ATGTGGACAGCCAGGACTCCATTGACTCGAACGACTCTGATGATGTAGATGACACTGA TGATTCTCACCAGTCTGATGAGTCTCACCATTCTGATGAATCTGATGAACTGGTCACT GATTTTCCCACGGACCTGCCAGCAACCGAAGTTTTCACTCCAGTTGTCCCCACAGTAG ACACATATGATGGCCGAGGTGATAGTGTGGTTTATGGACTGAGGTCAAAATCTAAGAA GTTTCGCAGACCTGACATCCAGTACCCTGATGCTACAGACGAGGACATCACCTCACAC ATGGAAAGCGAGGAGTTGAATGGTGCATACAAGGCCATCCCCGTTGCCCAGGACCTGA ACGCGCCTTCTGATTGGGACAGCCGTGGGAAGGACAGTTATGAAACGAGTCAGCTGGA TGACCAGAGTGCTGAAACCCACAGCCACAAGCAGTCCAAAGTCAGCCGTGAATTCCAC AGCCATGAATTTCACAGCCATGAAGATATGCTGGTTGTAGACCCCAAAAGTAAGGAAG AAGATAAACACCTGAAATTTCGTATTTCTCATGAATTAGATAGTGCATCTTCTGAGGT CAATTAAAAGGAGAAAAAAATACAATTTCTCACTTTGCATTTAGTCAAAAGAAAAAAT GCTTTATAGCAAAATGAAAGAGAACATGAAATGCTTCT ORF Start: ATG at 63 ORF Stop: TAA at 933 SEQ ID NO: 48 290 aa MW at 32606.4 Da NOV l la, MRIAVICFCLLGITCAIPVKQADSGSSEEKQ YNKYPDAVAT NPDPSQKQNL APQ CG I 10725- NAVSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDD 01 Protein SHQSDESHHSDESDELVTDFPTDLPATEVFTPWPTVDTYDGRGDSWYGLRSKSKKF RRPDIQYPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDD Sequence QSAETHSHKQSKVSREFHSHEFHSHEDMLWDPKSKEEDKHLKFRISHELDSASSEVN Further analysis of the NOVl la protein yielded the following properties shown in Table 1 IB

Similarly to methylene blue pretreatment, superoxide anion generation had no effects on base-line cyclic guanosine phosphate levels or cyclic guanosine phosphate responses elicited by S-nitroso-3-mercaptoproprionic acid

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