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Description

PI3K/AKT activation mediates cell survival and resistance to apoptosis through inactivation of the pro-apoptotic protein BCL-2 antagonist of cell death (BAD) and degradation of the pro-apoptotic protein p53 (Birchmeier et al., 2003)

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The Ames test showed no mutagenicity, chromosomal aberration assays detected no genotoxicity, and micronucleus testing revealed no clastogenic effects

"The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration." Journal of Applied Physiology