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There have been reports of a number of changes in the concentrations of several neuropeptides in PD brain, which are mainly significant decreases in (Jimnez-Jimnez, 1994): (a) met-enkephalin (MET-ENK), substantia P (SP), and cholecystokinine 8 (CCK-8) in the substantia nigra

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Consistent with these mechanistic differences, increased expression of key lipogenic genes, such as Fasn and Srebf1 , was prominent in MASLD but not MASH, both in murine models and in patient samples (56)

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People at higher risk for vitamin B12 deficiency include vegetarians, vegans, older adults, and those with digestive conditions that affect nutrient absorption