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The importance of AKT in cancer-related IGF signaling is further exemplified by its role in invasion and metastasis [33]

Ghrelin not only triggers appetite but also plays a key role in fat metabolism and muscle preservation

Intermittent and low-level inhibition of key UPS components, which triggered only very mild stress in the differentiating hMSCs, had surprisingly distinct effects on the bone-like material they formed, altering its stiffness and the amount of protein and crystalline mineral it contains, and affecting its micro- and ultra-structural organization (53)