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The synergistic effect of combination temozolomide and chloroquine treatment is dependent on autophagy formation and p53 status in glioma cells

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Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes

This wide range of concentrations in the non-diseased brain is likely to be a functional corelate, as suggested by the present findings

For example, ciclopirox exhibits anti-inflammatory activity by inhibiting the activity of iron-containing arachidonate 5-lipoxygenase (ALOX5) and prostaglandin endoperoxide synthase (PTGS/cyclooxygenase) ( Dexrazoxane Dexrazoxane is a cyclic derivative of EDTA that easily penetrates cell membranes

In the mass spectrum, we found species of m = 387.04 Da that correspond to the persulphide GSSO 3 H