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Combining substances can cause chemical reactions, "clumping," or pH changes that make the nutrients ineffective or unsafe

While sub-ILM delivery would allow donor RGCs to be sequestered within microns of their final positions in a nutrient-rich tissue, like SR injection, it would require extensive lateral migration of RGCs to subserve the peripheral retina

doi: 10.1038/srep46079 196 ZhaoYFengXChenYSelfridgeJEGorityalaSDuZet al

Aug 30 2017;9(9)doi:10.3390/nu9090960

The available evidence suggests that the AP mediates amylins satiating effect by reducing glucagon secretion and slowing gastric emptying