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acidic conditions limit drug uptake in breast cancer, 292 whereas in bladder cancer, CQ disrupts cholesterol metabolism and enhances cytotoxicity

She has authored more than 150 peer-reviewed publications and 15 invited articles, including reviews, editorials, commentaries, and perspectives, with over 70,000 citations, including numerous first-, senior-, and corresponding-author papers in top-tier and high-impact journals such as Nature (5), Nature Medicine (4), Cancer Cell (5), Cancer Discovery (4), Nature Biotechnology , Nature Genetics (2), The Lancet Oncology, Journal of Clinical Oncology, Gastroenterology, Gut (2) , Science Translational Medicine , and Nature Communications (10), as well as invited review articles in premier journals including Nature Reviews Molecular Cell Biology , Nature Reviews Clinical Oncology , Cancer Cell , Annual Review of Medicine , and Trends in Cancer

Fungsi glutathione bisa membantu meningkatkan sensitivitas tubuh dalam merespon insulin

Samples were washed x3 with cold argon-purged 50 mM HEPES buffer (pH 7.5), resuspended in 500 L washing buffer and exposed first to 1 mM TCEP, and after 3 min, 5 mM IAM was added and incubated for a further 20 min (Procedure A) or IAM-TPP (Procedure B) for 30 min at RT protected from light

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In addition, glutamate signal transduction in neurons is augmented by dopamine, therefore, nigral neurons, i.e., substantia nigra pars compacta neurons, are highly susceptible to glutamate excitotoxicity effects (85)