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This is especially so in singers, even though when done well, such surgery is extremely safe and voice restoring

Increased testosterone provides a negative feedback to the hypothalamus and pituitary, leading to reductions in both GnRH pulse frequency and pituitary responsiveness to GnRH, ultimately resulting in reduced gonadotropin release [37]

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Neuronal input triggers Ca2+ influx through AMPA receptors and voltagegated Ca2+ channels in oligodendrocytes

Krause BJ, Del Rio R, Moya EA, Marquez-Gutierrez M, Casanello P, Iturriaga R (2015) Arginase-endothelial nitric oxide synthase imbalance contributes to endothelial dysfunction during chronic intermittent hypoxia

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