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In the last few years, various GSH modulation-enhanced combinational therapy strategies have been extensively exploited, accompanied by the development of versatile metal-based nanosystems with different structures, functionalities, and treatment performances ( In view of the rapid development of GSH-responsive and -exhausting metal nanomedicines in potentiating cancer therapy, we summarize and outline the recent advancements, mechanisms, prospects, and challenges in this field from different strategies (Scheme 1)

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Quality control (QC) samples for resveratrol were prepared at the following concentrations: LLOQ QC (2.000 ng/mL), LQC (6.000 ng/mL), MQC2 (60.0 ng/mL), MQC1 (800 ng/mL), HQC (1600 ng/mL), and DQC (6000 ng/mL)

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Wang, T