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Problem: Increased Fine Lines or Wrinkles Temporary increase in fine lines during weeks two through six can reflect normal collagen remodeling

Furthermore, we discuss the recent detection of methylation biomarkers in clinical samples such as blood, urine, sputum, feces, and tissues

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15 Skin, Hair & Tissue Integrity Hormones influence collagen production, skin elasticity, hair growth cycles, and wound healing, changes many women notice during menopause

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Sharif et al., 2012) (see Table 1)