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10.1194/jlr.M300529-JLR200 71 SantistebanM

A study that evaluated 101 adults diagnosed with CVS showed that 86% of the cohort were women.3 Regarding race, 78% were White, 17% were African-American, and 5% were Hispanic.3 CVS is associated with numerous comorbidities, such as migraine, generalized anxiety disorder, panic disorder, major depression, autonomic dysfunction, and cannabis use.1012 The probability of presenting with a psychiatric comorbidity in adults with CVS is 40-times higher than in the general population, and the most frequent are anxiety (69%) and depression (48%)

Sometimes, such cramps are initiated by making a movement that shortens the muscle

Biomacromolecules 26, 57915806

Interestingly, this enzymatic reaction was extensively investigated by Krebs (1935) in several tissues including the brain

Neuroleptic Malignant Syndrome (NMS): A potentially fatal symptom complex may occur with administration of antipsychotic drugs, including ARISTADA INITIO and ARISTADA