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These non-enzymatic antioxidants, whether from diet or synthesized for therapy, vary in effectiveness against human cancer, showing both successes and failures in use [62,63,64]

NAD+ is essential for cellular energy production and its levels decline up to 50% between ages 40 and 60

Furthermore, various regulators have also been elucidated involved in ubiquitination-mediated ferroptotic modulation, providing potential pharmacological therapeutic targets[59, 60]

Matrix metalloproteinase-2 and -9 activities in the human lens epithelial cells and serum of steroid induced posterior subcapsular cataracts

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[DOI] [PubMed] [Google Scholar] 131.Yu G, Nishimura M, Arawaka S, Levitan D, Zhang L, Tandon A, Song Y-Q, Rogaeva E, Chen F, Kawarai T, Supala A, Levesque L, Yu H, Yang DS, Holmes E, Milman P, Liang Y, Zhang DM, Xu DH, Sato C, Rogaev E, Smith M, Janus C, Zhang Y, Aebersold R, Farrer L, Sorbi S, Bruni A, Fraser P, and StGeorge-Hyslop P