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(2020) reported its involvement in erastin-induced ferroptosis, but the specific regulatory upstream and downstream relationships are still unclear

10.3389/fnut.2023.1288202 25 GoujonG.BaldimV.RoquesC.BiaN.SeguinJ.PalmierB.et al (2021)

It mediates the 1:1 exchange of glutamate and cystine

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5 is the increase of urea cycle intermediates (arginine, ornithine, citrulline, and argininosuccinate), as well as other linked amino acids (lysine, proline, asparagine, and glutamic acid)