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Intriguingly however, very recent data on anti-CD20 B cell depleting agents might be showing some efficacy in progressive MS, although the effect of peripheral B cell depletion on PIRA cannot be interpreted as independent of its effect on silencing acute/adaptive inflammatory activity (Kappos et al., 2020)

A double-blind controlled trial of unselected cases published in 1962 gave no support to the belief that systemic vitamin B12 is of any value in the treatment of psoriasis, single or combined with a bland ointment, a dithranol regime, or a modified Goeckermann regime [129]

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Together, spontaneous healing after 8 weeks means that temporal muscle detachment in monkeys represents only a mild course [18]

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