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10.1371/journal.pone.0207374 216 NematisouldaraghD.KirshenbaumE.UzonnaM.KirshenbaumL.Rabinovich-NikitinI

Sustained IGF-I elevation from any GH secretagogue raises theoretical concerns IGF-I is a mitogen, and chronic elevation is a variable of interest in tissue-growth contexts that have not been evaluated for this blend over time

Dysfunction of this system, often resulting from chronic stress or poor sleep quality, leads to the accumulation of toxic metabolites, which is a hallmark of neurodegenerative diseases