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Both catabolic pathways of histamine via histamine-N-methyltransferase and diamine oxidase are diminished in the colonic mucosa of patients with food allergy

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However, the importance of correcting reductive stress is illustrated by the finding that in three Manchester patients with recurrent acute pancreatitis, who were referred after the trials, standard treatment failed: the addition of folate to provide more methyl groups did not help, but a choline supplement did (JM Braganza unpublished)

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Di Cristo F, Calarco A, Digilio FA, Sinicropi MS, Rosano C, Galderisi U, Melone MAB, Saturnino C, Peluso G (2020) The discovery of highly potent THP derivatives as OCTN2 inhibitors: from structure-based virtual screening to in vivo biological activity

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(2015) Factors Associated With Problems for Adolescents Returning to the Classroom After Sport-Related Concussion

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