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Human cohorts are often set up before specific research questions or purposes are fully defined

Exercise has been shown to be effective in controlling ADHD symptoms, [and] has essentially no side effects. While thats not really true, [I]t should be noted that a major difference in the two treatment modalities is that medications have a defined effect on ADHD symptoms alone, whereas exercise produces physical, mental, and emotional advantages that are far-reaching. So, exercise does have side effects, but theyre all good

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Int J Gen Med (2021) 14:1011729

Therefore, targeting TMAO could be a way to treat DKD