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Abdominal fat increases intra-abdominal pressure, forcing stomach contents upward against the lower esophageal sphincter

There are other synthetic peptides that have not been well tested, often because early studies found they were not effective or are potentially toxic

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The inactivation of this protein leads to the inhibition (stopping) of neurotransmitter and neuropeptide release from the nerve endings and the prevention of the electrical pain signals from firing off

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