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It plays key roles in energy production, DNA repair, circadian rhythm, and cellular communication

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R min and R max are defined as the corresponding R values with 0 and saturating GSH concentrations, respectively

(49) showed that in a 6-OHDA-induced N27 cell model pretreated with EGCG, intracellular ROS and HO levels were significantly reduced, Nrf2 nuclear translocation was promoted, and HO-1 and NQO1 expression was increased, thereby enhancing antioxidant enzyme activity and reducing oxidative damage and apoptosis

In people over the age of 65, the prevalence of PD is approximately 1%