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Serotonin is a neurotransmitter found primarily in thegastrointestinal tract, platelets and central nervous system

Most CRC cases are sporadic and progress from adenoma to carcinoma through multiple genetic and epigenetic alterations (Song et al., 2020)

10.1371/journal.pone.0288523 83 JiangR.DuX.LnnerdalB

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The effects of melatonin are mediated by two types of G-protein-coupled receptors (MT1 and MT2) located in various parts of the brain and peripheral tissues, such as the liver, pancreatic and cells, adrenal glands, blood vessels, and gonads [75]

Carnitine is an amino acid metabolite naturally made in the body