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Abstract An array of enzymes and metabolites is responsible for maintaining plant cellular redox homeostasis by counteracting excessive oxidant production

Variants reduce enzyme efficiency, leading to oxidative stress, hypertension, and vascular injury

To maintain a steady, endogenous supply of cysteine for glutathione production, the body relies heavily on the transsulfuration pathway

The homogenate was then centrifuged at 1300 g for 3 min at 4 C

Here we discuss the main ideas involved in modeling the transsulfuration pathway, referring the reader to [20] (and its online supplementary material) for a discussion of the other parts of the model

10.1186/s12915-020-00775-7 25 BamblingM.EdwardsS