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Description

2023 Aug 20:205:291-304

Mitochondrial fatigue, where cells are not producing energy efficiently, responds to MOTS-c, often layered with NAD+ therapy

Methods: Retrospective study of patients with cirrhosis and ascites from a single quaternary centre from Apr 2020 to Mar 2021 identified patients who fulfilled the 2015 International Ascites Club (IAC) diagnosis of AKI

While the half-life of Nr1i3 mRNA is approximately 6.6h, the half-life of CAR protein remains unknown and could be investigated in primary hepatocytes in future experiments (75)