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Further investigation showed that CPs first reduce the level of skin oxidation, inhibit the expression of the key transcription factor AP-1 (c-Jun and c-Fos), then activate the TGF-/Smad signaling pathway to promote collagen synthesis, inhibit the expression of MMP-1/3 to inhibit collagen degradation, and inhibit skin inflammation to alleviate skin aging in mice

[5] Figure 1, demonstrates how histidine is metabolised into histamine, in which it is broken down via two pathways using the enzyme diamine oxidase (DAO) and or histamine- N -methyltransferase (HNMT)

Plasma samples (1 l) were chromatographed on 4%20% SDS-PAGE (BioRad, Hercules, CA)

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Abstract Background Depletion of glutathione (GSH) stores is associated with preterm birth and is not corrected by neonatal supplementation with N-acetylcysteine (NAC), a GSH precursor

28 , 588604.e585 (2018)