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Pulmonary drug delivery via nebulization has documented advantages over DPIs, as it allows for greater delivery of the drug to the lungs, and may be suitable for patients with COPD who have difficulty using DPIs because of coordination difficulties and low inspiratory flow rates (e.g., elderly patients) [17]

Lorente-Cantarero, F.J

PubMed:9849822 Andersen, N.B., et al

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Drug-receptor interactions in anaesthesia