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acnes produces porphyrins, an inflammatory compound that produces acne

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Indeed, the SCCNVs could be produced by inducing senescence ex vivo in the cancer cells of patients and after several steps of purification, SCCNVs could be re-injected into the patients

Cartilage faces even greater obstacles given avascular nature (no blood vessels penetrating tissue), low cell density (chondrocytes sparse within extensive extracellular matrix), minimal metabolic activity (slow turnover and repair), and mechanical loading challenges (constant stress impeding healing)