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We also unfortunately could not perform subgroup analysis for all endpoints due to limited numbers of trials examining the particular endpoints

Front Fungal Biol 2:733492 Kumar AU, Ling APK (2021) Gene introduction approaches in chloroplast transformation and its applications

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Excess iron can drive oxidative stress , essentially creating internal "rust", which damages cells, contributes to inflammation, and ironically impairs detoxification

However, selenium should not be routinely supplemented in non-deficient individuals [55, 63], in particular because chronic excess may lead to toxicity (selenosis)