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Interferon- (IFN-) predominantly acts through the JAK1/2-STAT1 pathway to induce M1 polarization, enhancing the expression of other proinflammatory factors such as IL-6 and tumor necrosis factor- (TNF-), with TNF- being a potent promoter of M1 polarization as well as a significant inhibitor of M2 polarization [47]

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Subjects in any one or more of the following categories were excluded from our analysis: (1) the presence of type I or II diabetes, (2) active viral and/or bacterial infection, and (3) received high-dose glucocorticoid pulse therapy

Host-directed targeting of lincRNA-MIR99AHG suppresses intracellular growth of mycobacterium tuberculosis

However, the regulatory mechanism of ferroptosis has not been fully elucidated and the investigation still faces challenges

plasmid #48138) and was used to transfect 3T3-L1 cells with Cas9 along with the targeting guide RNAs (gRNAs)