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Key Safety Differentiators No IGF-1 elevation: AOD-9604 does not stimulate IGF-1, meaning it avoids risks such as organ/tissue overgrowth or acromegaly No glucose disruption: Clinical data shows it does not impair insulin sensitivity or worsen blood sugar regulation Comparable to placebo: In obesity trials, the incidence of adverse effects was similar to placebo groups, underscoring its tolerability Legal Status of AOD-9604 United States: AOD-9604 is not FDA-approved as a drug, dietary supplement, or weight loss therapy

Nrf2-MafG heterodimers contribute globally to antioxidant and metabolic networks

Nature 499 , 485490 (2013)

100.66 Dhs

Conclusion : Pseudo-septic hip arthritis as the presenting features of AS has been quite rare but may be expected in the juvenile onset variant

BW, body weight