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Recent research on mutations in MT-CO1, MT-CO2, and MT-CO3 in tumors has typically approached these genes as a combined group, rather than examining them in isolation [60, 79, 85]

Biochemically, once ferroptosis is activated, it cannot be suppressed by apoptosis, necrosis, or autophagy inhibitors but can be hidden by iron chelators such as deferoxamine (DFO) or antioxidants such as Trolox and fer-1

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