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Usage: Target Species: Dogs, cats, and horses Indications: Treatment and prevention of vitamin B-complex deficiencies Support during periods of stress, illness, or recovery Administration: Administer via intramuscular (IM), subcutaneous (SC), or intravenous (IV) injection

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Leaving It at Room Temperature Reconstituted MOTS-C degrades rapidly above refrigerator temperature

Comment: A commenter sought CMS guidance on its plans to ensure consistency across the Medicare Shared Savings Program (MSSP) in applying the revised definitions, providing updated technical specifications and training resources, and monitoring the impact of these changes on MSSP performance scores

The difference between vial and pen storage primarily relates to air exposure: vials with unused doses can be re-capped and re-refrigerated between uses, while pens are single-use devices that must be discarded once opened, even if medication remains

Neurologic complications are not always associated with megaloblastic anemia and are the only clinical symptom of vitamin B 12 deficiency in about 25% of cases (21)