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Confinement hinders motility by inducing RhoA-mediated nuclear influx, volume expansion, and blebbing

Clinical trials would need to assess both hemodynamic parameters and clinical outcomes including walking distance, pain scores, and amputation rates to establish therapeutic benefit

Unlike regular pharmacies that sell pre-manufactured drugs, compounding pharmacies can put prescribed drugs into custom topical treatments, injectables, flavored liquids, and more at specified doses