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2009;34(9):HS-14-HS-18

Toxicological studies have demonstrated that the oral LD 50 of the aqueous leaf extract exceeds 6,000 mg/kg, highlighting its wide margin of safety

Additionally, exposure to PM 2.5 upregulates the expression of fibrosis-related proteins (e.g

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Cyanogenic glycosidessuch as linamarin, linustatin, neolinustatin, lotaustralin, and amygdalinare nitrogenous metabolites that can be converted by intestinal -glycosidase into cyanohydrin, which breaks down into hydrogen cyanide

However, activation of RLR signalling is inhibited by very efficient HCV NS3/4A-mediated MAVS cleavage 28,29 , which was not affected by D1467G (Fig