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Fan Y, Lu X, Chen X, Wang J, Wang D, Wang S, Guo L, Rui C, Zhang Y, Cui R, et al

Additionally, ATF3 promotes macrophage polarization towards the M2 phenotype, enhances the expression of anti-inflammatory factors such as Arg-1 and PPAR, but suppresses M1 markers (such as iNOS and TNF-), thereby alleviating inflammatory responses and facilitating tissue repair (142)

Like any supplement, you should check with your healthcare provider before using it

The results showed that after transfection with siSTAT3, GHK-Cu treatment showed a synergistic effect on the inhibition of inflammatory factors (Figures 8AE)