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Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine

PQQ also enhance the activation of nuclear respiratory factors (NRF-1, NRF-2) and transcriptional activation of Tfam, TFB1M, and TFB2M, which are linked with the activation of the PGC-1 pathway

This condition is characterized by abdominal pain, irregular bowel movements, bloating, and other digestive issues

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