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Those with Pernicious Anemia This autoimmune condition affects the bodys ability to absorb B12

(2015a) reported in another study that IL-23 and IL-17 serum levels and expression of mRNA of IL-23 P19, IL-23 P40, and IL-17 in CNS were significantly reduced in EAE mice treated with 200 mg/kg ginger compared to control

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If you are deficient, your cells are essentially starving for energy, leading to that heavy, lead-like fatigue