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GERD develops when this sphincter weakens or relaxes inappropriately, allowing stomach acid to irritate the delicate esophageal lining

Evidence shows that mouse neurons are highly sensitive to GPX4 depletion, which results in a lethal phenotype 84

doi: 10.1371/journal.pone.0293700 74 GongYJiPYangY-SXieSYuT-JXiaoYet al

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Ferroptosis is morphologically and mechanistically distinct from other PCD, such as apoptosis, necrosis, pyroptosis, and autophagy [15, 16]

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