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Experts on Konzo who are based at the University of Kinshasa and Institute National de Research Biomedical (INRB) helped design and execute the research activities presented in this manuscript, in collaboration with the large group of co-authors who aided in research activities related to this work

Conclusion: The data strongly suggest that in contrast to the report that UDCA is a gut FXR antagonist, in this study, UDCA seems to act as an FXR agonist, especially in the ileum

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VD obtained by sunlight exposure or through diet is converted to the main circulating form of VD, 25(OH)D, by 25 hydroxylase