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We have received approval for the collection of information associated with the virtual group election process under OMB control number 0938-1343 (CMS-10652)

FIGURE 5 In vitro inhibition of oxidative stress in human alveolar epithelial cell by GHK-Cu via the upregulation of Nrf2 level After applying 5% CSE into A549 cells for 24 h, we found that the MDA level was increased, and the levels of T-AOC and GSH were decreased compared with those in A549 cells without CSE exposure, indicating that CSE stimulates an increase in oxidative stress in human alveolar epithelial cells

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JAMA (2020) 323(6):548

In addition, we also carried out the same analysis on a more simple warhead compound (PK_test), which was the C2 ester analogue of the warhead moiety present in 1a R -IN-8 (referred to as compound 3 in ref

doi:10.3174/ajnr.A6543 111