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By comparison, oral B12 supplements are absorbed at roughly 1 to 5% in healthy adults, and even less if you have low intrinsic factor, atrophic gastritis, celiac disease, Crohn's, or a history of gastric bypass

Older adults with food-cobalamin malabsorption , where the stomach acid needed to release B12 from food has dropped with age

Avoid long-term use unless prescribed by a healthcare provider due to potential risks such as bone fractures or vitamin B12 deficiency

Depending on the severity and location of the nerve damage, this condition can lead to symptoms such as numbness, tingling, burning sensations, or facial pain [1]

However, the body is generally very efficient at excreting excess B12 through urine without any issues