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An increase in IGF-1 in the circulation, in the liver and also in the muscle was observed in the Goat -/- mice, either as a result of the disordered GH pulse pattern, or because there was a failure of the elevated IGF-1 levels to feedback on GH release

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112 YangH.YanR.ChenQ.WangY.ZhongX.LiuS.et al (2023)

Zinc translocation accelerates infarction after mild transient focal ischemia