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In addition, the cytoprotection was independent of the antioxidant status of the catalase and glutathione peroxidase enzymes, suggesting a direct interaction between creatine and oxidant and/or free radicals

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Available from: Heintjes EM, Berger M, Bierma-Zeinstra SMA, Bernsen RMD, Verhaar JAN, Koes BW

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This study found that heat hyperalgesia was decreased with TRPV1 antagonism and that TRPV1 expression in large neurons in the trigeminal ganglia was increased