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Instead, it is designed solely to activate the innate repair receptor (IRR) , the bodys primary switch for tissue protection and anti-inflammation.According to research published in Molecular Pain , ARA-290 is disease-modifying. It works by quieting microglia , the immune cells in the nervous system that drive chronic pain when overactive

Subcutaneous formalin and intraplantar carrageenan increase nitric oxide release as measured by in vivo voltammetry in the spinal cord

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Grossart HP, Frindte K, Dziallas C, Eckert W, Tang KW (2011) Microbial methane production in oxygenated water column of an oligotrophic lake PNAS

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