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Description

Gao J, Chow EWL, Wang H, Xu X, Cai C, Song Y, et al

R.StoneA

The therapeutic approach centers on isoform-selective inhibitors or genetic silencing, complemented by pathway co-targets that feed these enzymes (e.g., angiotensin/PKCNOX axes) and precision delivery to the relevant plasma-membrane, endosomal, or nuclear microdomain to avoid off-target suppression of host defense (Cipriano et al