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189 Management of DRPN focuses on optimizing glycemic control to prevent further nerve damage

Because immunotherapy drugs have only been used in the clinic for a short time, there are few studies on immunotherapy resistance caused by FAO metabolic reprogramming

PLOS One 11, e0165130

Also, though used as a last resort, the spleen might be surgically removed in cases where the red blood cells are so affected that the spleen removes them from the blood too quickly for other treatments to compensate

Moreover, obesity has been revealed to reduce the effectiveness of TNF inhibitors, resulting in lower chances of achieving remission or low disease activity (58, 60)