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2019 Oct 17;11(10):2494

Accepted: Published: Version of record: Issue date: DOI:

Surg Obes Relat Dis 9(2):323327 Suliburska J, Cofta S, Gajewska E, Kalmus G, Sobieska M, Samborski W, Bogdanski P (2013) The evaluation of selected serum mineral concentrations and their association with insulin resistance in obese adolescents

Prolonged oxidative stress impairs insulin-induced GLUT4 translocation in 3T3-L1 adipocytes

What they found: Darkening of existing nevi in 85 % of patients New nevi in 30 % Atypical features on dermatoscopy in 40 % Two cases of malignant melanoma in the followed cohort No evidence of a causal relationship, but associative correlation Why it matters: These are the most serious published safety data for Melanotan II