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doi: 10.1242/jcs.071340

Lys 337 in the B chain (cyan) is covalently linked to PLP

These enzymes include those with mononuclear iron centers, such as the prolyl hydroxylases that regulate hypoxia-inducible factors (Nandal et al., 2011) or dinuclear iron centers, such as deoxyhypusine hydroxylase (Frey et al., 2014)