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The research findings confirm the study's aim and "strongly suggest involvement of developmental signaling pathways and mechanisms, including EndoMT, in the pathogenesis of canine MMVD." Most significantly, the findings suggest that, instead of MVD being a degenerative condition, MVD may be due to the development of EMT and EndoMT

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These findings suggest that circulating histidine levels may not be solely determined by the dietary intake but could also reflect microbial histidine production and consumption 57,85

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zdemir R, Gzel O, Kk M, Karadeniz C, Katipoglu N, Ylmaz , Ylmazer MM, Mee T