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Shimizu T, Kato T Jr, Tachibana A, Sasaki MS

In preclinical models of neurodegeneration, GLP-1R agonists reduce amyloid plaque formation, improve neuronal survival, and reduce neuroinflammation

High basolateral glucose increases sodium-glucose cotransporter 2 and reduces sirtuin-1 in renal tubules through glucose transporter-2 detection

In addition, analysis of p53-induced apoptosis in a human colon cancer cell line showed that elevated p53 expression was associated with an elevation of GPx1 [31, 32]